Development of resistance results from mutations in the viral genome, and the presence of selective drug pressure leads to the emergence of a resistant virus population.The aim of this study was to analyze the impact of genetic variability on the genetic barrier to drug resistance to DAAs.The genetic barrier was quantified based on the number and t
This study aims to design an electric bell and determine the kinesthetic improvement ability of visually impaired people after using the Dewey Decimal Classification (DDC) listicv bell as an information #syd-hill-oilskin-Full Length guide.When a visitor wants to know the braille book, title, location, and classification of Dewey (DDC) then it is ne
Here we embark in a deep metagenomic survey that revealed the taxonomic and potential metabolic pathways aspects of mangrove sediment microbiology.The extraction of DNA from sediment samples and the direct application of pyrosequencing resulted in approximately 215 Mb of data from four distinct mangrove areas (BrMgv01 to 04) in Brazil.The taxonomic
Hepatocellular carcinoma (HCC) represents a global health concern, ranking as the sixth most common malignancy worldwide and the third leading cause of cancer-related mortality.Despite advances in research, the diagnosis and prognosis of such malignancy remain challenging.Alpha-fetoprotein, the current serum biomarker used in the management of HCC,
BACKGROUND: Maternal diabetes alters gene expression leading to neural tube defects (NTDs) in Charging cradles the developing brain.The mechanistic pathways that deregulate the gene expression remain unknown.It is hypothesized that exposure of neural stem cells (NSCs) to high glucose/hyperglycemia results in activation of epigenetic mechanisms whic